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Regarding A metabolism, several miRNAs including miR-9, miR-29, miR-135, and miR-186 are significant regulators of Beta-Secretase 1 ( BACE1) enzyme levels which is central in A generation (Wang et al., 2019)

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doi: 10.1016/j.braindev.2018.12.007 [PubMed] 30921018 VanHaerents S, Gerard EE

But the same mechanisms that make these drugs effective can also cause gastrointestinal side effects such as: Nausea Vomiting Diarrhea Reduced appetite All of these symptoms can contribute to lower fluid intakeor increased fluid losswhich is a fast track to dehydration

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