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Not everyone experiences fatigue, and the intensity can vary

All clinical trial protocols used once-weekly subcutaneous injection

Fatigue and decreased energy levels affect some users, particularly during the first few weeks

The most frequently reported issues include: Nausea : 21.49% of patients Diarrhea : 10.62% Vomiting : 9.10% Dyspepsia (indigestion) : 8.67% Constipation : 7.92% Decreased appetite : 5.49% While many tolerate these medications well, over 10% of patients stop or interrupt treatment due to severe discomfort

The analogy from physicians is that this would be equivalent to providing blood pressure medication through 2027 and then asking patients to return to uncontrolled hypertension