Without a gallbladder, your intestinal transit time and fat digestion are already disrupted
Metabolic goals semaglutide still provides strong benefits for blood sugar and heart health
Over time, consistently skipping medication leads to: HbA1c rising above target Silent damage to kidneys, eyes and nerves Higher risk of heart attack and stroke Faster progression to needing insulin Never skip medication without consulting your doctor
The most common side effects of GLP-1 receptor agonists are gastrointestinal symptoms including nausea, vomiting, diarrhoea, and abdominal discomfort, particularly during treatment initiation
Gastroenterology research and practice
Both classes slow gastric emptying, but tirzepatide has shown particularly potent effects on gastric motility, especially after the initial 5mg dose