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The presence of chronic health conditions like heart disease, high blood pressure, and kidney disease also plays a significant role when deciding on an appropriate GLP-1 medication

Semaglutide is FDA-approved for type 2 diabetes management (Ozempic, Rybelsus), cardiovascular risk reduction in patients with type 2 diabetes and established cardiovascular disease (Ozempic), chronic weight management in obesity or overweight with comorbidities (Wegovy), and cardiovascular risk reduction in adults with established cardiovascular disease and obesity or overweight (Wegovy)

Around 24 to 30 percent of the weight lost can be lean mass

CNNs Meg Tirrell and Tami Luhby contributed to this report.

The most evidence-supported approach to muscle preservation is dietary protein not supplements

If youre not reaching your weight or blood sugar targets, discussing Mounjaro with your prescriber is reasonable