However, it quickly began apparent that one notable effect was the ability of semaglutide to also cause decreases in weight
Dr Kamal Kant Kohli-MBBS, DTCD- a chest specialist with more than 30 years of practice and a flair for writing clinical articles, Dr Kamal Kant Kohli joined Medical Dialogues as a Chief Editor of Medical News
doi: 10.1016/j.bbrc.2019.01.103 49 BomfimTRForny-GermanoLSathlerLBBrito-MoreiraJHouzelJCDeckerHet al
Experimental evidence indicated that while peptides bound to albumin do not penetrate the CNS, peripheral activation of the GLP-1R system would be coupled to neuronal activation and central effects of gastric emptying and decreased food intake, independent of direct exposure on the CNS [47]
However, new research is raising an important question: could GLP-1 therapies help break that cycle
To reduce GLP-1 side effect risk, start with smaller meals, eat more slowly, and keep very fatty foods moderate while your dose increases