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According to the Centers for Disease Control and Prevention (CDC), long-term success often requires a combination of nutrition, physical activity, behavioral changes, and the appropriate medical interventions

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At the same time, it clearly highlights the limit: effects are moderate, gradual and in no way comparable to drugs that directly and long-term activate GLP-1 receptors [1][3][5]

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99 Another 8-week aerobic exercise intervention demonstrated an 11.92% and 45.45% increase in serum total osteocalcin and undercarboxylated osteocalcin levels, respectively, in the exercise group, and no dramatic changes were observed in the control group