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The skin is first carefully assessed and marked if needed to ensure even coverage

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Based on a randomized, placebo-controlled pilot study (Preprint: Hawkins et al., 2024)

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Interestingly, while the role of GSTs has classically been associated to the modification of small molecules and the role of glutaredoxins to the deglutathionylation of proteins, it has recently been shown that human GSTO1-1 can deglutathionylate -actin, which should prompt us to consider proteins as GST substrates (Menon and Board, 2013)

But at the end of the day, I am a clinician