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EPP is the primary approved clinical indication for Afamelanotide and has generated the most extensive translational research programme characterising MT-1s photoprotection mechanisms in human subjects

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Trends Immunol 38(1):519 Pinsornsak P, Kanokkangsadal P, Itharat A (2015) The clinical efficacy and safety of the sahastara remedy versus diclofenac in the treatment of osteoarthritis of the knee: a double-blind, randomized, and controlled trial