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A 2023 study published in JAMA found that GLP-1 receptor agonist users were 3.7 times more likely to develop gastroparesis compared to users of bupropion-naltrexone (another weight-loss drug)

It can be synthesized from the amino acid citrulline through the breakdown of body proteins or obtained through dietary protein intake from foods like meat, poultry, dairy, nuts, fish, and soy products

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