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In agreement with this, kinetic modelling suggests that MDHAR will be the predominant contributor to ascorbate regeneration (Polle 2001)

Cochrane.Database.Syst.Rev

Genetic polymorphisms in NAT2 (N-acetyltransferase 2), TPMT (thiopurine methyltransferase), and glutathione S-transferase genes create phenotypic differences

Alaofi AL

Benzbromarone has been linked to potential hepatic toxicity and cardiovascular risk, whereas probenecid may exhibit significant central nervous system toxicity and hypersensitivity syndrome, particularly when administered at higher dosages

It was also found to aid recovery from brain injury