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By week two, most people notice the nausea becoming less intense

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Instead, the challenge is much more likely to be managing the turmoil created by seasonal cycles of binge-and-abstain behaviour influenced by intermittent GLP-1 use

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23 The other is made right inside the brain, mostly in preproglucagon neurons of the caudal hindbrain, specifically the nucleus tractus solitarius (NTS) and the adjacent intermediate reticular nucleus