A 2024 clinical trial in chronic rhinosinusitis failed, highlighting the risks associated with indication expansion
Once you stop taking them, symptoms like insulin resistance and weight gain often come back
5 mg Vials (Twice Weekly) 8 weeks 3 vials (~10.2 mg total) 12 weeks 4 vials (~18.2 mg total) 16 weeks 6 vials (~26.2 mg total) 2 mg Vials (Once Weekly) 8 weeks: 8 vials (1 vial/week) 12 weeks: 12 vials (1 vial/week) Insulin Syringes (U-100) Twice Weekly: 2 syringes/week 8 weeks: 16 syringes , 12 weeks: 24 syringes , 16 weeks: 32 syringes Once Weekly: 1 syringe/week 8 weeks: 8 syringes , 12 weeks: 12 syringes Bacteriostatic Water (10 mL bottles) Use 1.0 mL per 2 mg vial or 2.0 mL per 5 mg vial for reconstitution
Heres what a U-shaped curve looks like (data points are invented for illustration purposes): Photo by Innerbody Research In this invented example, the intervention in question does its best job at reducing a negative biomarker at around 200mg, after which the effect tapers off and soon becomes almost nonexistent
Pernicious anemia occurs when the body lacks intrinsic factor, a protein needed to absorb vitamin B12 from food
Visible Alpha consensus around $10B
