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doi:10.1016/j.canlet.2013.08.017 67

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The most common side effect of melanotan II is appetite suppression, but it should not be as significant as one might associate with diet or fat loss medications, the site says

Chronic flat GH exposure saturates hepatic IGF-1 production, desensitizes peripheral GH receptors, and drives water retention, carpal tunnel syndrome and insulin resistance at higher frequencies than pulsatile signaling does