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Clinicians should exercise caution in patients with a history of pancreatitis or gastroparesis, inflammatory bowel disease, other gut motility disorders, medullary thyroid carcinoma, or Multiple Endocrine Neoplasia syndrome type 2, and pause therapy when clinically indicated, such as before anesthesia

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It functions as an active endocrine organ, constantly secreting hormones and inflammatory molecules that wreak havoc on your metabolism

These findings emphasise that whilst the absolute risk remains relatively low, it is measurably increased compared to those not undergoing treatment, making monitoring and patient education essential components of safe prescribing practice