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These resources recommend that clinicians consider B12 deficiency in any patient presenting with relevant symptoms or risk factors, and that treatment particularly intramuscular hydroxocobalamin should not be delayed pending specialist review when deficiency is confirmed and symptomatic, especially where neurological involvement is present

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Retatrutide is an investigational triple agonist activating GLP-1, GIP, and glucagon receptors simultaneously, producing greater weight reduction than single or dual agonists

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