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Binding activates adenylate cyclase through Gs alpha coupling, elevating intracellular cyclic AMP and triggering the release of stored growth hormone (GH) from secretory granules

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unlike earlier GHRP generations, Ipamorelin stimulates the release of growth hormone (GH) from the anterior pituitary without significantly impacting ACTH, prolactin, follicle-stimulating hormone (FSH), luteinizing hormone (LH), or cortisol levels

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