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Cysteine, glutathione, and thiol redox balance in astrocytes

In summary, we highlight the importance of PSPH genetic alterations in GBM in promoting tumor aggressiveness and immunosuppression, which could be effectively targeted by a novel combinatorial therapeutic strategy of sertraline plus chloroquine

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In some cases, healthcare providers may adjust the frequency, for example, some patients might be advised to take the injection twice weekly or once every two weeks, depending on their specific goals and how they respond to treatment