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Gastrointestinal Research

It is well affirmed from recent experimental findings that interleukin 6 (IL-6) signaling via STAT-3 contributes to repression of foxp3 transcription, so the probable repression of IL-6 signaling by statins may indirectly support foxp3 expression, leading to an improved proportion of Treg cells [62]

At present, the potential of new substances to cause sensitization is determined from the results of tests on animals or sometimes on humans (Rycroft, 1995), after databases have been searched for relevant published information

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