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A potential paradigm shift in managing severe hypertriglyceridemia and metabolic liver disease beyond GLP-1 therapy

However, sulforaphanethrough its well-characterized activation of the NRF2 pathway and enhancement of cellular antioxidant responsesmay reduce oxidative post-translational modifications that facilitate -syn aggregation

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Some foods that are otherwise well-suited, including aged cheeses, fermented foods, cured meats, certain fish, and some nuts, are also high in histamine or histamine liberators

Genetic testing can reveal specific mutations that impact histamine metabolism, and personalized strategies can be developed to manage symptoms

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