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It is not simple

The most commonly reported side effects were digestive in nature primarily nausea, diarrhea, and constipation and were mostly rated mild to moderate

Effects of liraglutide on clinical stability among patients with advanced heart failure and reduced ejection fraction: a randomized clinical trial

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Only 15.3% of included studies reported whether patients experienced GI side effects with additional symptoms, and 6.8% serious GI complications like pancreatitis and severe nausea and vomiting (exclusively in studies of GLP-1 receptor agonists)

Most of our patients begin seeing measurable results within the first 4 to 8 weeks