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Supplementary Information Supplementary Video 1

Moreover, LKB1 loss has been linked to increased serine metabolism [8]

Experimental receptor binding assays indicate that Cagrilintide can activate both amylin receptor subtypes and the calcitonin receptor itself, producing measurable signaling responses in cellular assay systems

This effect of HFD was not observed until 24 weeks after insulin resistance, which resulted in less liver fibrosis

If you experience unusually large hematomas, spreading bruises, or bruising that doesn't fade within 2-3 weeks, notify your providerthis may indicate a bleeding or vascular issue requiring evaluation before continuing GLP-1 therapy