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Here, we discovered that prolonged treatment of colon cancer cells with IGF-1R inhibitors (BMS-754807 and GSK1838705A) stimulates p70 KDa ribosomal protein S6 kinase 1 (p70S6K1) activation, a well-known kinase signaling for cell survival

We investigate thyroid dysfunction, low cortisol, B12 deficiency, anemia, low testosterone, mitochondrial dysfunction, infections, and sleep disruption