Firmicutes bacteria are commonly linked to gut dysbiosis in prediabetic and obese individuals, which were overwhelmingly dominant in both groups' microbiomes at the start of the study (representing more than 90% of the subjects' total sampled bacteria)
Results indicated ~20% of these individuals had a germline mutation in a DNA repair gene, including BRCA1/2, PALB2, and the Lynch syndrome genes, among Permanent link to this article: ICARE Newsletter Winter 2019 Expansion of Lynch Syndrome Tumor Spectrum Which May Have Treatment Implications ICARE Newsletter Winter 2019 Expansion of Lynch Syndrome Tumor Spectrum Which May Have Treatment Implications Although the Lynch syndrome tumor spectrum is thought to be limited to cancers of the colorectum, endometrium, ovaries, stomach, and a few other cancer types, a recent article suggested there might be a broader tumor spectrum than previously considered
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