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It binds directly to GHRH receptors on somatotroph cells in the anterior pituitary, enhancing both the amplitude and duration of GH secretion

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SLU-PP-332 is a preclinical research compound that acts as a PAN-ERR agonist to mimic aerobic exercise gene expression

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Perhaps the largest is that while the trial was large, with 17,604 participants, it did not enroll a diverse group of participants