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Finally, vitamin B12 is crucial for the biochemistry of the nervous system, participating in DNA synthesis, methionine synthesis, methylation reactions, myelin synthesis, and neurotransmitter production (42, 70, 73, 77)

However, genetic mutations and modern ills like poor diet, chronic stress, and exposure to toxins can affect the body's ability to manufacture adequate levels of glutathione and lead to glutathione deficiency

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Yang, R.K., et al., Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity

Immunity 21(1):8193 Shajahan-Haq A, Cook K, Schwartz-Roberts J, Eltayeb A, Demas D, Warri A et al (2014) Glutamine metabolism and the unfolded protein response in MYC-driven breast cancer

The trans effect determines the polarizability of the CoC bond so formed