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GPX4 protects adipocytes from lipid peroxidation, oxygen-specific epitope accumulation, and ferroptosis

2023;66(July): 102849

Heliyon 2023;9:e18491 20 Zheng Z, Zong Y, Ma Y, Tian Y, Pang Y, Zhang C, et al

The trade-off: you don't get the metabolic benefits of pulsatile GH (lipolysis spikes, acute insulin sensitivity modulation), and the constant IGF-1 elevation creates steady negative feedback to the hypothalamic-pituitary-somatotropic axis

In NBJ's Feb

Additionally, because semaglutide affects glucose metabolism, it helps stabilize blood sugar levels, which can be particularly beneficial for individuals with type 2 diabetes