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The limited available human clinical evidence evaluating BPC-157 and related peptide therapies in musculoskeletal settings is summarized in Table 2

Recent comparative evolutionary analysis of ABHD5 and closely related paralog ABHD4 identified critical surface residues of R299 and G328 that are required for lipase activation of PNPLA2, which can be dissociated from translocation of PNPLA2 (34)

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