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Maybe it's like two days a week to really get the maximum effect

If you're on 10 mg vials and ramped too fast, the fix is often the opposite drop back, switch to every-other-day dosing, and let receptors stabilize before going up again

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Niswender K, Pi-Sunyer X, Buse J, et al

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The abundance of erythrocytes in circulation suggests that immunogenic consequences of their cell death might dictate the immune response in disease, which is an underappreciated but important feature of erythrocyte biology