How to structure and execute a zone 2 workout [59:45]
VEGF is a signaling protein that triggers angiogenesis, the formation of new blood vessels
During sleep, cells repair DNA damage, build proteins, and regenerate tissues
The same applies to oral vitamin C bioavailability is roughly 3050% from oral doses, compared with near-100% intravenously, and blood concentrations achievable via IV simply cannot be reached orally
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The source of WS is the Werner (WRN) DNA helicase gene, which regulates the transcription of the essential NAD+ biosynthetic enzyme Nicotinamide Nucleotide Adenylyltransferase 1 (24,25). NAD+ depletion through disruption of mitochondrial homeostasis is a substantial contributor to the metabolic dysfunction in WS, according to a 2019 study (25)