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74 A previous study has demonstrated that SGLT-2 is present in the central nervous system, including the brain parenchymal and the BBB

Sometimes, however, a drugs dose can be so variable that the manufacturer provides a sufficient quantity in the single-use vial to accommodate a wide range of amounts

The inhibitory effect is presumably mediated indirectly through somatostatin secretion, but a direct effect cannot be completely excluded

In type 2 diabetes mellitus, portal vein insulin levels are elevated to compensate for the insulin-resistant state of the body

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