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In these approaches, at the first step, a large set of static random models of various possible conformations of a given protein is computationally generated, from which a sub-ensemble of conformations that collectively describe the experimental profile is selected (Kikhney and Svergun, 2015)

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53.3 5.7 years) were excluded (remaining n = 13), there was a borderline statistically significant effect, with pomegranate extract reducing TMAO log AUC by 15% compared with placebo