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It is characterized by recurrent abdominal pain associated with altered bowel habits, including diarrhea (IBS-D), constipation (IBS-C), or mixed patterns (IBS-M)

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When the barrier between the gut and the bloodstream weakens, bacterial fragments and other compounds can cross where they do not belong, and the immune system responds

Jang et al., Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation

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