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The EMA said at the time that its Pharmacovigilance Risk Assessment Committee (PRAC) was analysing around 150 reports of suicidal thoughts and thoughts of self-injury

The blood-labyrinth-barrier (BLB), which includes a blood-endolymph barrier and a blood-perilymph barrier, consists of tight junctions between specialized epithelial cells in the labyrinth spaces (i.e., the vestibular and cochlear spaces)

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The mitochondrial membranes are rich in polyunsaturated fatty acids, making them highly susceptible to a specific type of oxidative damage known as lipid peroxidation