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Gut Journal reported that GLP-1s may reduce chemotherapy side effects like mucositis

224 Physiological properties of the body, including organ mass and volume, blood flow rate, plasma protein levels, and the abundance of enzyme and transporter expression, are mathematically described within the model

For example, in a clinical trial for Wegovy, 4% of adults who have type 2 diabetes and a BMI over 27 (considered overweight) developed diabetic retinopathy, a potential complication of diabetes that leads to blood vessel damage in the retina

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This effect was largely abolished by AMD3100 but not by YIL781 or TAK-779, further implicating the CXCR4 pathway

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