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This article is here to educate, not to replace medical advice

As VLDL particles lose triglycerides, they transform into LDL particles

Methylene-THF dehydrogenase 2 (MTHFD2) is subsequently responsible for the production of 10-formyl-THF, which is mostly exported and regenerated in the cytosol to participate in purine biosynthesis (Yang and Vousden, 2016)

Medication is prescribed at provider discretion and is one possible component of a larger protocol

Many EHRs now connect to PBMs to retrieve a patients out-of-pocket cost for a drug before prescribing