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Moreover, TQ exhibits a significant level of safety, even when administered at a dosage of 90 mg/kg (111)

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*Correspondence: Changyu Li, [email protected] This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

However, many of these drugs were associated with unexpected adverse effects, such as nausea, aversion, valvular heart disease, and even suicidal tendencies, leading to the discontinuation of most of their development

They were noted to have increased myelinated nerve fibers, leading to a greater brain weight than those mice without liraglutide

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