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Leading companies such as Novo Nordisk, Eli Lilly, and Sanofi have contributed to market growth with innovative products, including once-weekly formulations to improve patient adherence

Yet analysts noted a glimmer of hope: the therapy reduced mucus buildup in most patients, a potential early sign of clinical benefit that could emerge with higher doses or longer treatment

Among them, 4-HNE-modified proteins [39] and MDA-modified proteins [40] are the most commonly studied

While pills are often destroyed by the digestive system, liposomal formulas use a phospholipid bilayer to protect the glutathione and deliver it directly to the cells.