why is tirzepatide being discontinued In a 69-year-old man who discontinued tirzepatide (Zepbound) after six months and now has worsening depression and concerns about weight regain, what pharmacologic Weight-Loss Drug Tirzepatide Can Keep

Bulletin of Experimental Biology and Medicine, 133(3), 274276

In the SUSTAIN-6 trial, semaglutide was associated with a significant increased risk of diabetic retinopathy complications, including vitreous hemorrhage, blindness, or conditions requiring treatment with an intravitreal agent or photocoagulation (HR 1.76, 95% CI 1.112.78) [27]

Other impulse-driven categoriessuch as sweet baked goodsshow a similar but slightly more moderate impact profile, while center-of-store staples and household essentialslike dry beans, rice, pasta and cerealstend to be relatively more resilient

Is Tirzepatide approved for long-term use

(Wegovy, another GLP-1, is FDA approved for weight loss.) GLP-1 is a naturally occurring hormone that tells the pancreas to release insulin needed to lower blood sugar levels

Stauder U, Enginee D, Elton H, Penfornis A, Edelman S