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Furthermore, as OLGc are the predominant iron-containing cells in the brain and highly susceptible to ferroptosis, their demise may increase local iron, predisposing to FIN (Nobuta et al., 2019

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Structurally, semaglutide is similar to human GLP-1 but modified to resist degradation by enzymes such as dipeptidyl peptidase-4 (DPP-4), prolonging its biological activity and effectiveness in controlling blood glucose and reducing body weight

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