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doi: 10.1371/journal.pone.0079167 27 SzaboCColettaCChaoCModisKSzczesnyBPapapetropoulosAet al

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Hyperlipidemia is primarily responsible for atherosclerosis, where elevated oxidized low-density lipoprotein (LDL) levels, as well as glucose and free fatty acids, are detected in patients with atherosclerosis, diabetes, and obesity [68]

This and many other forms are not serious but respond well to antihistamines and topical steroids , neither of which will cure the reaction but can help treat symptoms