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137 For instance, a study has reported that IL1 or TNF-induced acetylation of H4K5Ac, H4K8Ac, and H4K12Ac mediates the recruitment of the BET proteins, BRD3 and BRD4, to the matrix degrading enzyme gene promoter, consequently upregulating their expression in human chondrosarcoma cells

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When the team compared results from the surviving animals to the control group, they found no difference in pancreatic weights, insulin-positive beta cell proportions or overall pancreatic vascularity