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Pucciarelli, G., Mastursi, M., Latte, S., Sacra, C., Setaro, A., Lizzadro, A., and Nolfe, G

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Other differences between lipedema and lymphedema include symmetry (lipedema tissue occurs symmetrically versus lymphedema, which is usually unilateral), sparing of the hands and feet in lipedema, and report by patients of pain in lipedematous but not lymphedematous tissue

The assessment of neuronal activation using cFos as a surrogate marker in response to an acute administration of cagrilintide and sCT in chow-fed mice revealed that both cagrilintide and sCT produced a significantly higher cFos signal compared to vehicle-treated mice, showing similar activation patterns in WT mice AP, NTS and LPBN brain areas

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