Between 2018 and 2023, the number of patients taking a SGLT2 inhibitor medication and the number of patients undergoing cardiac catheterization are inversely related
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One notable barrier is that GLP-1 receptor agonists have historically been administered via SC injection only
Equivalence and Oversight Health Canada described generic semaglutide as a complex synthetic product that is pharmaceutically equivalent to the brand name biologic drug, and said its review ensures differences between products do not affect safety, efficacy, or quality [Source: canada.ca/en/health-canada/news/2026/05/canada-approves-second-generic-semaglutide-the-first-g7-country-to-do-so.html]
Even after these medications are on the market, they are still monitored, which includes assessing the impact of long-term use
In major clinical trials, GLP-1s were linked to fewer strokes, heart attacks, and other serious heart issues, even for people taking other heart medications