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Because the nasal dosage forms of Vitamin B 12 have a lower absorption than intramuscular dosage, nasal dosage forms are administered weekly, rather than the monthly intramuscular dosage

After the acute repletion phase, therapy is usually transitioned to an oral maintenance multivitamin containing a physiological dose of pyridoxine (2-5 mg daily) for several weeks, along with dietary counseling to prevent recurrence

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In rats that received NO-agents, L-arginine methyl ester (L-NAME

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