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The textbooks describe a clear hierarchy of approaches: Steps that begin with general dental care: Prompt biopsy of any suspicious pigmented oral lesion, with histopathological examination and immunohistochemistry (S-100, HMB-45, SOX10, MART-1) to confirm the diagnosis

Over time, patients may lose fat while maintaining muscle mass, creating a leaner physique even when the scale changes slowly

In studies, participants lost an average of 15% body weight over 68 weeks

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Most people don't realize the difference between helpful fullness and problematic early satiety