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Symptoms are worsening despite conservative treatment

Genomic instability and catalase gene amplification induced by chronic exposure to oxidative stress

doi:10.1080/10606820213687

Studies show that being overweight or obese can make psoriatic arthritis symptoms worse, and losing weight may improve swelling in the joints, fatigue, and pain

These reductions represented estimated treatment differences ranging from 3.0% to 7.8% weight loss versus placebo, all of which were statistically significant

At the ingredient level, berberine has been studied for its potential effects on blood sugar regulation, lipid metabolism, and cellular energy pathways