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Biochem J 353:411416

Semaglutide, tirzepatide, and liraglutide are FDA-approved GLP-1 peptides that are clinically safe and effective for diabetes and weight management

Holmes, R

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The content of melanin in melanocytes was increased by maclurin in a dose-dependent manner, by a mechanism involving the activation of the cAMP/PKA/CREB signaling pathway, which in turn increased tyrosinase, MITF and their downstream TRP-1 and Trp-2 protein content, while also involving the activation of p38 MAPK and p44/42 MAPK pathways

Discussion Here, we showed that the intermediate metabolite -KG controls the translation of energy sensor AMPK in human liver and lung cancer cells to maintain cell survival under energy stress