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10.1007/s10522-009-9236-0 Summary Keywords 3D cell culture, adipose tissue engineering, in vitro modeling, lipedema, pathogenesis Citation Soni K and Abbott RD (2026) New Frontiers in modeling the lipedema microenvironment in vitro

ParkerJLDemeJCKolokourisDKuteyiGBigginPCLeaSMet al

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This route delivers higher hippocampal concentrations with lower systemic exposure, reducing peripheral side effects while maintaining therapeutic receptor activation longer at the target site