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Mutations in the glutathione synthetase gene cause 5-oxoprolinuria
The Bcl-2/Bax ratio increased and cleaved caspase-3 levels dropped, indicating reduced apoptosis (Pyo et al., 2007)
[DOI] [PubMed] [Google Scholar] 98.Esteller M., Corn P.G., Urena J.M., Gabrielson E., Baylin S.B., Herman J.G
Nakayama Y, Mukai N, Kreitzer G, Patwari P, Yoshioka J
Minoxidil also upregulates VEGF, but through a different pathway: potassium channel opening and prolyl hydroxylase inhibition (Lachgar et al., 1998)
Consider baseline labs for copper and zinc and reassess if symptoms or labs shift
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