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J Biotechnol 10(261):194206 Szczeklik K, Krzysciak W, Domagala-Rodacka R, Mach P, Darczuk D, Cibor D, Pytko-Polonczyk J, Rodacki T, Owczarek D (2016) Alterations in glutathione peroxidase and superoxide dismutase activities in plasma and saliva in relation to disease activity in patients with Crohns disease

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This means a subcutaneous injection in the abdomen can, and likely does, influence tissues throughout the body, including a damaged ankle

If endometriotic lesions rely on aberrant metabolism for survival, medications that correct metabolic dysfunction could theoretically undermine the metabolic support those lesions depend on